Polygenicity shapes brain connectivity in psychiatry

Authors: Clara A. Moreau, …, Pierre Bellec, and Sebastien Jacquemont

September 2021

Interactive brainmaps (mean beta values per region (atlas MIST64, Urchs et al, 2019)

GSA: global signal adjusted

https://github.com/claramoreau9/NeuropsychiatricCNVs_Connectivity/

1q21.1

## DEL with GSA

## DUP with GSA

## DEL without GSA

## DUP without GSA

13q12.12

## DEL with GSA

## DUP with GSA

## DEL withou GSA

## DUP without GSA

15q11.2

## DEL with GSA

## DUP with GSA

## DEL without GSA

## DUP without GSA

16p11.2

## DEL with GSA

## DUP with GSA

## DEL without GSA

## DUP without GSA

16p13.11 DUP

## DUP with GSA

## DUP without GSA

17p12 DEL

## DEL with GSA

## DEL without GSA

22q11.2

## DEL with GSA

## DUP with GSA

## DEL without GSA

## DUP without GSA

Idiopathic psychiatric conditions

#ASD with GSA

#ASD without GSA

#SZ with GSA

#SZ without GSA

#Bipolar with GSA

#Bipolar without GSA

Polygenic scores GSA

#Polygenic scores for schizophrenia with GSA

#Polygenic scores for schizophrenia without GSA

#Polygenic scores for autism with GSA

#Polygenic scores for autism without GSA

#Polygenic scores for major depression with GSA

#Polygenic scores for major depression without GSA

#Polygenic scores for IQ with GSA

#Polygenic scores for IQ without GSA